General info

• Introductory meeting: Oct 15, 2013, time 14:00-16:00 , room 001 cluster building E1.7
• Block seminar: March 19th - March 20st, 2014, 9:00 till 16:00, room 008 cluster building E1.7. Reports have to be handed in until the 12th of March 2014.
• You get 7 credit points
• Master students are eligible
• Limit of 15 participants
• Required to follow the seminar: Basic knowledge of genetics
• Recommended lectures: Bioinformatics 1-3, The Elements of Statistical Learning I or Machine Learning
• This seminar can serve as an in-depth follow-up to the lecture Bioinformatics for Next Generation Sequencing
• Registration: Please send an email to mschulz at mpi-inf.mpg.de (topic: seminar Advanced Topics in Next Generation Sequencing Analysis)

Course overview

Next Generation Sequencing (NGS) methods have revolutionized genetics. Applications of these technologies to e.g. genome or transcriptome sequencing create computationally challenging analysis problems. This seminar covers recent literature about new algorithmic and statistical developments for different problems in the analysis of NGS data. Some of the topics covered will be algorithms for de novo assembly, detection of differential expression and human genomic variations,sequencing error correction. Every student will give a 45 minute presentation on the assigned topic and will also hand in a report of 10 - 12 pages.