Structural Bioinformatics (WS 2013/14)
Structural Bioinformatics (WS 2013/14)
News
- 2014-01-20 Preliminary list of questions for the exam (questions covering lectures 14 and 15 will be added)
- 2014-01-20 The last lecture of the course is moved from February, 5 to Jaunary, 30, 2014, 10:00, room 001 (E2.1).
- 2013-11-20 Date for the first exam is set: February, 14, 2014, 10:00, room 007 (E2.1).
- 2013-10-22 Tutorials: Thursdays on bi-weekly basis from 16:00 till 18:00 in E2.1, room 003. First tutorial on 2013-10-24.
- 2013-10-08 The first lecture will take place on 2013-10-16 in E2.1, room 007
General information
Lecturer | |
Language | English |
Course description |
Structural bioinformatics studies protein structures resolved in 3D by experimental methods. recent years have witnessed an exponential growth of experimental data on protein structure and interactions due to projects such as Structural Genomics Initiative. This opens new venues for bioinformatics studies related to protein structure prediction, comparison and analysis. The course will takes you from the very basic concepts of how structural data are obtained and organized in databases to sophisticated topics of intricate relationships between protein structure and function and the evolution of the two; and insights from comparison of protein structures. In the exercises, we will learn basic techniques for structure search, comparison, analysis of active residues, protein modelling and small molecule docking. |
Master students are eligible |
|
Prerequisites | Bioinformatics I, II |
Recommended reading | The course is largely based on "Structural Bioinformatics", 2nd edition, eds. Jenny Gu, Philip E. Bourne. Where appropriate, the material from the book will be supplemented with data from recent literature. These will be made available in the password protected area. |
Time and location
Lecture |
Wednesday, 12:00 - 14:00, Campus E2.1 (CBI building), room 007 |
Tutorial |
Biweekly, slot to be decided |
Office hours |
Olga Kalinina: after each lecture |
Course material
Lecture slides and tutorial handouts are available in the password protected area.