Ekaterina M. Myasnikova, David Kosman, John Reinitz, and Maria G. Samsonova
Abstract
The application of image registration
techniques resulted in the construction of an integrated atlas
of Drosophila segmentation gene expression in both space and time.
The registration method was based on a quadratic spline approximation
with flexible knots. A classifier for automatic attribution of
an embryo to one of the temporal classes according to its gene
expression pattern was developed.