Structural aspects in bioinformatics of viruses

Structural aspects in bioinformatics of viruses (WS 2015/16)


  • 2016-04-12 Second exam: April 13, 2016, 14:00-18:00, room 001 E2 1. Please fill in the poll to allocate your time slot
  • 2016-02-01 First exam: Feb 12 and Feb 19, 2016, both dates 12:00-16:00, room 001 E2 1. Second exam: April 13, 2016, 14:00-18:00, room 001 E2 1.
  • Questions to help you study for the exam
  • 2015-10-14 First lecture: Oct 26, 12:15, room 001 E2 1; first tutorial session: Nov 3, 16:00, CIP-pool

General information


Olga Kalinina



Course description

Studying viruses with methods bioinformatics is a growing field of research. Due to their unique structure, life cycle, and evolution, viruses present a significant challenge to established methods of analysis.

In this course we will first consider the basics of virology: what is known about virus particle structure, their replication, interactions with the host cell, and finally their origin. The course will also introduce the most important methods, algorithms and resources of structural bioinformatics, and put them into the context of virus research. The topics will include: protein structure determination and analysis; protein and nucleic acid structure prediction and comparison; structure-based evolutionary and functional analysis; drug design.

Master students are eligible


Bioinformatics I, II

Recommended reading

The course is partly based on "Structural Bioinformatics", 2nd edition, eds. Jenny Gu, Philip E. Bourne. Additionally, I recommend to consult a basic virology textbook of your choice. A lot of material from the recent literature is used. These will be made available in the password protected area.

Time and location


Monday, 12:00 - 14:00, Campus E2.1 (CBI building), room 001
First lecture will be held on October 26, 2015 in E2.1, room 001


Tuesdays on bi-weekly basis from 16:00 till 18:00 in E2.1, room 003. First tutorial on 2015-11-03

Office hours Olga Kalinina: after each lecture

Course material

Lecture slides, tutorial handouts, and problem sets are available in the password protected area.