Olga Kalinina

English

Studying viruses with methods bioinformatics is a growing field of research. Due to their unique structure, life cycle, and evolution, viruses present a significant challenge to established methods of analysis.

In this course we will first consider the basics of virology: what is known about virus particle structure, their replication, interactions with the host cell, and finally their origin. The course will also introduce the most important methods, algorithms and resources of structural bioinformatics, and put them into the context of virus research. The topics will include: protein structure determination and analysis; protein and nucleic acid structure prediction and comparison; structure-based evolutionary and functional analysis; drug design.

Master students are eligible

Bioinformatics I, II

The course is partly based on "Structural Bioinformatics", 2nd edition, eds. Jenny Gu, Philip E. Bourne. Additionally, I recommend to consult a basic virology textbook of your choice. A lot of material from the recent literature is used. These will be made available in the password protected area.

Monday, 12:00 - 14:00, Campus E2.1 (CBI building), room 001
First lecture will be held on October 26, 2015 in E2.1, room 001

Tuesdays on bi-weekly basis from 16:00 till 18:00 in E2.1, room 003. First tutorial on 2015-11-03