Structural Bioinformatics (WS 2014/15)

Structural Bioinformatics (WS 2014/15)


  • 2015-01-30 First exam date: 9.2.2015, 13:00, room 001 E2 1
  • 2015-01-30 Second exam date: 24.4.2015, 14:00, room 007, E2 1
  • 2015-01-28 The list of questions for the exam
  • 2014-10-31First practical assignment is online, due Nov 5, 2014, 12:00. Revisions to be discussed during the tutorial Nov 13, due Nov 19. Reports to be submitted via e-mail as PDFs!
  • 2014-10-31Essays due Christmas, 2 to 4 pages, to be submitted via e-mail as PDFs!

General information


Olga Kalinina



Course description

Structural bioinformatics studies protein structures resolved in 3D by experimental methods. recent years have witnessed an exponential growth of experimental data on protein structure and interactions due to projects such as Structural Genomics Initiative. This opens new venues for bioinformatics studies related to protein structure prediction, comparison and analysis.

The course will takes you from the very basic concepts of how structural data are obtained and organized in databases to sophisticated topics of intricate relationships between protein structure and function and the evolution of the two; and insights from comparison of protein structures. In the exercises, we will learn basic techniques for structure search, comparison, analysis of active residues, protein modelling and small molecule docking.

Master students are eligible


Bioinformatics I, II

Recommended reading

The course is largely based on "Structural Bioinformatics", 2nd edition, eds. Jenny Gu, Philip E. Bourne. Where appropriate, the material from the book will be supplemented with data from recent literature. These will be made available in the password protected area.

Time and location


Wednesday, 12:00 - 14:00, Campus E2.1 (CBI building), room 007
First lecture will be held on October 22, 2014 in E2.1, room 007


Thursdays on bi-weekly basis from 16:00 till 18:00 in E2.1, room 003. First tutorial on 2014-10-30

Office hours Olga Kalinina: after each lecture

Course material

Lecture slides and tutorial handouts are available in the password protected area.